CBD for Hemorrhoids

Hemorrhoids are among the most common diseases of the rectum, affecting over half of all adults at some point in their lives. Symptoms such as anal itching, burning, bleeding, or pain when sitting can significantly impair quality of life. While conventional therapies—such as those using cortisone preparations or surgical procedures—are effective in many cases, they often reach their limits in cases of sensitive mucous membranes or chronic conditions. Cannabidiol (CBD), a non-psychoactive compound from the hemp plant, offers a modern, well-tolerated, and locally effective alternative. In the form of rectal suppositories—CANNEFF® SUP—CBD is combined with hyaluronic acid. CANNEFF® SUP has anti-inflammatory, itch-relieving, and mucosa-protective effects—without the side effects of cortisone-containing products. This article examines the causes, symptoms, and standard therapies for hemorrhoids and explains how CBD can be used specifically to combat irritation in the anal area. The focus is on the application, the advantages over classic preparations, and the possible uses of CANNEFF® SUP for acute symptoms, maintenance therapy, and mucosal care after surgical procedures.
Philip Schmiedhofer, MSc

Autor

Philip Schmiedhofer, MSc

Inhaltsverzeichnis

What are hemorrhoids and how do they manifest?

Hemorrhoids are well-vascularized, sponge-like vascular cushions in the anal canal that are present in every person.

What causes and risk factors contribute to hemorrhoids?

The development of hemorrhoidal disease is caused by multiple factors.

Conventional Treatment of Hemorrhoids – and Its Limits

The treatment of hemorrhoidal disease depends on the severity of the symptoms and the degree of hemorrhoids, which are classified into four stages.

CBD for Hemorrhoids: How Cannabidiol Works in the Anal Area

Cannabidiol (CBD), a non-psychoactive compound from the hemp plant, is gaining increasing importance in the treatment of inflammatory diseases, including in the area of anal and rectal health.

The Benefits of CBD Suppositories for Hemorrhoids

CBD suppositories are a modern, locally effective, and well-tolerated treatment option for hemorrhoids, especially for internal hemorrhoids and inflammatory irritations in the lower rectum.

CBD or cortisone for hemorrhoids – which is better tolerated?

Cortisone preparations (glucocorticoids) are an important part of the standard treatment for acute or inflamed hemorrhoids.

CANNEFF® suppositories with CBD and hyaluronic acid for hemorrhoids?

CANNEFF® SUP rectal suppositories are specially designed for use on irritated, inflamed, and sensitive mucous membranes in the anal and rectal area.

Does CBD help with post-itching, burning, and hemorrhoid pain?

Itching, burning, and pain in the anal area are the most common and unpleasant symptoms of hemorrhoidal disease.

When is CBD useful for hemorrhoids – and when is it not?

CBD is a sensible and well-tolerated option for hemorrhoids, especially when inflammatory symptoms, mucous membrane irritation, or itching are prominent.

What are hemorrhoids and how do they manifest?

Hemorrhoids are well-vascularized, sponge-like vascular cushions in the anal canal present in every person. They serve to finely close the anus and help control the retention of stool. Only when these vascular cushions enlarge, become inflamed, or protrude outward is it medically referred to as hemorrhoidal disease, commonly shortened to "hemorrhoids."

Anatomy and classification

They are distinguished between:

  • Internal hemorrhoids
    They lie above the so-called linea dentata, i.e., in the inner anal canal. Since they are located in a less sensitive mucous membrane area, they are initially painless.

  • External hemorrhoids
    They develop below the linea dentata in a highly sensitive skin area. They can be very painful, especially with thrombosis or irritation.

Although the topic is embarrassing for many affected individuals, hemorrhoids are widespread. Over half of all adults over 30 suffer from them at some point in life. If left untreated, they can lead to chronic discomfort, mucous membrane irritation, or inflammatory changes, so early diagnosis and targeted treatment are recommended.

Symptom

Description

Anal itching

Often the first sign – caused by irritation, moisture, or mild inflammation

Burning in the anal area

Especially after bowel movements or prolonged sitting

Bright red blood in the stool

Bleeding during bowel movements – typically visible on toilet paper

Foreign body sensation

Pressure or a "lump" sensation in the anal area

Oozing or mucus discharge

Due to impaired sealing of the anal canal

Pain when sitting

Especially with external hemorrhoids or thrombosis

What causes and risk factors promote hemorrhoids?

The development of hemorrhoidal disease is multifactorial. Although hemorrhoids are a natural part of the rectum, certain lifestyle and health conditions can cause excessive strain and enlargement of the vascular cushions. This subsequently leads to discomfort. Mechanical pressure, reduced blood flow, and irritants promote this process.

Risk factor

Mechanism

Chronic constipation

Straining during bowel movements increases pressure in the anal area

Prolonged sitting on the toilet

Causes blood to pool in the hemorrhoidal cushions and promotes vessel dilation

Lack of exercise

Poor bowel motility, venous congestion in the pelvic area

Low-fiber diet

Leads to hard stool and increased straining pressure

Overweight

Strains the pelvic floor and venous system

Pregnancy and childbirth

Hormonal changes and increased pressure on the pelvic floor

Frequent heavy lifting

Increased intra-abdominal pressure strains the vascular cushions

Age

With increasing age, connective tissue loses elasticity

Genetic predisposition

Weak connective tissue can occur more frequently in families

Not all causes can be avoided, but preventive measures such as a high-fiber diet, adequate fluid intake, exercise, and mindful toilet habits can significantly reduce the risk. When pressure on the anal mucosa is reduced, hemorrhoidal disease can often be prevented or at least significantly alleviated.

Conventional treatment of hemorrhoids – and its limits

The treatment of hemorrhoidal disease depends on the severity of symptoms and the stage of hemorrhoids, which are divided into four stages. In the early stages I and II, conservative measures usually take precedence, while in advanced cases (stage III–IV), surgical interventions may also be necessary. The goal of every treatment is to relieve symptoms such as itching, burning, bleeding, and pressure sensation, to relieve the vascular cushions, and to prevent relapses.

Hemorrhoid stages

Therapy type

Example agents / procedures

Purpose of use

Ointments and creams

Cortisone, zinc, lidocaine, witch hazel

Anti-inflammatory, pain relief, itch control

Suppositories & suppositories

Mesalazine, cortisone, local anesthetics

Treatment of internal hemorrhoids and mucous membrane irritation

Sclerotherapy (hardening)

Injection of sclerosing substances

Shrinking internal hemorrhoids (especially stage I–II)

Rubber band ligation

Tying off hemorrhoids

Cutting off blood supply (stage II–III)

Surgical procedures (hemorrhoidectomy)

Laser, stapler, open surgery

Removal or repositioning of advanced hemorrhoids

Despite numerous methods, many affected individuals report incomplete or only short-term relief as well as side effects or recurrences. Standard treatments reach their limits especially with recurring, painful, or inflamed hemorrhoids.

  • Possible side effects of topical preparations include thinning of the mucous membrane or promoting infections with long-term use of cortisone.
  • Insufficient effect on sensitive mucous membranes. Many products irritate instead of soothing.
  • High relapse rate after procedures. Hemorrhoids often recur, especially after ligations or surgeries.
  • There is no causal therapy. Most procedures only treat symptoms, not inflammation, irritation, or mucous membrane damage sustainably.
  • Burden from repeated treatments. For many patients, repeated medical procedures are psychologically and physically stressful.

Against this background, interest is growing in gentle, locally acting, and well-tolerated alternatives such as CBD (cannabidiol). Especially rectal CBD suppositories with hyaluronic acid like CANNEFF® SUP are gaining importance because they act anti-inflammatory, soothing, and mucous membrane-regenerating – all without cortisone or systemic burden.

CBD for hemorrhoids: How cannabidiol works in the anal area

Cannabidiol (CBD), a non-psychoactive compound from the hemp plant, is gaining importance in the treatment of inflammatory diseases, including in the area of anal and rectal health. Especially for inflamed or irritated hemorrhoids, CBD can be a valuable addition to conventional therapy. It acts locally as an anti-inflammatory, pain-relieving, and anti-itch agent and supports mucous membrane regeneration without the side effects of cortisone preparations. CBD exerts its effects through the endocannabinoid system (ECS), which plays a central role in regulating inflammation, pain perception, immune processes, and tissue healing. Since receptors of this system are also found in the anal region and rectal tissue, CBD can target these areas specifically.

Through rectal or perianal application – for example in the form of suppositories or creams – CBD reaches the site of discomfort directly, without detouring through the liver or digestive system. This reduces the dose burden and increases local effectiveness.

Mechanism of action

Relevance for hemorrhoids

Anti-inflammatory

Reduction of swelling, redness, and irritation of vascular cushions

Analgesic (pain-relieving)

Inhibition of pain receptors (e.g., TRPV1) – especially in irritation & thrombosis

Antipruritic (against itching)

Relief of histamine-mediated reactions – soothes irritated mucous membranes

Vascular stabilizing.

Can improve local microcirculation and reduce excessive blood congestion.

Regenerative.

Promotes healing of the sensitive anal mucosa through antioxidant effects.

Products combining CBD with hyaluronic acid, such as CANNEFF® SUP suppositories, have proven especially effective. They not only support anti-inflammatory effects but also improve the moisture and elasticity of the mucous membrane. This is particularly beneficial for irritated hemorrhoids.

The advantages of CBD suppositories for hemorrhoids.

CBD suppositories are a modern, locally effective, and well-tolerated treatment option for hemorrhoids, especially for internal hemorrhoids and inflammatory irritations in the lower rectum. They act directly on the irritated, inflamed mucous membrane. In combination with hyaluronic acid, as in CANNEFF® SUP, they also support the regeneration and moisturizing of the mucous membrane.

Advantages of CBD suppositories for hemorrhoids.

  • Direct effect at the site of inflammation.
  • Without systemic side effects like cortisone.
  • Well tolerated, even with sensitive skin and mucous membranes.
  • Relieves typical symptoms such as burning, itching, pressure, and pain.
  • Promotes mucous membrane healing thanks to hyaluronic acid.

CBD suppositories are a valuable addition to conventional therapy, especially for recurring or chronic complaints – also for maintenance therapy after acute flare-ups.

CBD or cortisone for hemorrhoids – which is better tolerated?

Cortisone preparations (glucocorticoids) are an important part of the standard treatment for acute or inflamed hemorrhoids. They have strong anti-inflammatory effects and quickly relieve itching and swelling. However, they are not suitable for long-term use, as frequent or continuous application can lead to unwanted side effects on the mucous membrane. CBD (cannabidiol) offers a milder and well-tolerated alternative. It is especially suitable for sensitive patients, chronic conditions, or maintenance therapy. In the form of suppositories with additional hyaluronic acid, as in CANNEFF® SUP, CBD acts anti-inflammatory and regenerative.

CANNEFF® suppositories with CBD and hyaluronic acid for hemorrhoids?

CANNEFF® SUP rectal suppositories are specially designed for use on irritated, inflamed, and sensitive mucous membranes in the anal and rectal area. For hemorrhoids, especially when symptoms such as itching around the anus, burning, oozing, or mucous membrane irritation are prominent, they offer a modern, well-tolerated, and locally effective support. The unique combination of cannabidiol (CBD) and hyaluronic acid provides a dual effect: CBD acts anti-inflammatory, anti-itch, pain-relieving, and antioxidant. Hyaluronic acid moisturizes the mucous membrane, protects it from mechanical irritation, and supports its natural regeneration. This synergistic effect makes CANNEFF® SUP an ideal option—both in the acute phase and in long-term care for chronic or recurring complaints. CANNEFF® SUP is especially recommended for internal hemorrhoids with signs of inflammation, anal itching, oozing mucous membranes, or postoperative irritation. The patented emulsion matrix ensures effective absorption of the active ingredients in the mucous membrane. Even during phases without acute symptoms, it can be used for regeneration and stabilization of the mucous membrane, for example as part of maintenance therapy. The product, available without a prescription in Austria, is an excellent steroid-free alternative or complement to classic treatment.

CANNEFF® SUP impresses with its good tolerability, the absence of irritating additives, and the ability to sustainably care for even sensitive mucous membranes without the risks associated with classic corticosteroid preparations. Thus, it represents an effective, gentle, and safe solution for those affected by hemorrhoids, suitable for use in both acute and chronic cases.

How are CANNEFF® SUP suppositories used for hemorrhoids?

The application is simple and discreet. The suppository is inserted rectally, ideally in the evening before going to bed, when the body is at rest and absorption through the rectal mucosa can occur optimally. Hands should be washed thoroughly beforehand. Disposable gloves can be used if needed. The suppository is carefully removed from the foil and, if necessary, slightly moistened. Then it is inserted deeply into the anus in a side-lying position with legs slightly bent. Afterwards, a calm lying position should be maintained for about 15 to 30 minutes. The recommended dosage is one suppository per day over a period of several days to weeks, depending on the symptoms and tolerance.

Does CBD help with anal itching, burning, and hemorrhoid pain?

Anal itching, burning, and pain are the most common and unpleasant symptoms of hemorrhoidal disease. Often, there is also oozing, irritation, or a feeling of pressure. The symptoms arise from inflammatory reactions, a disturbed mucosal barrier, and mechanical stress on the sensitive anal region. CBD (cannabidiol) is a better alternative to conventional remedies like cortisone-containing ointments or local anesthetics. It not only provides temporary relief but is also better tolerated and plant-based.

CANNEFF® SUP has anti-inflammatory, anti-itch, pain-relieving, and antioxidant properties. It works through the body's own endocannabinoid system, which is also active in the anal mucosa. There, it specifically regulates the response to stimuli, inflammation, and pain signals. The rectally applied CBD suppositories allow targeted action of the active ingredient at the affected site without burdening the gastrointestinal tract. The combination with hyaluronic acid, as contained in CANNEFF® SUP Rectal Suppositories, is particularly effective. Patients report rapid and significant improvement of the distressing symptoms. This is especially true for chronically irritated or sensitive anal mucosa. Improvement occurs particularly after frequent bowel movements, hard stool consistency, or during periods of increased strain, such as prolonged sitting. Anal itching and burning will noticeably decrease, pain when sitting or after using the toilet will lessen, and the mucosal sensation will also improve significantly.

Unlike cortisone, CANNEFF® SUP does not cause mucous membrane thinning, dependency effects, and can also be used long-term – provided there is no contraindication.

When is CBD useful for hemorrhoids – and when is it not?

CBD is a sensible and well-tolerated option for hemorrhoids, especially when inflammatory symptoms, mucous membrane irritation, or itching are prominent. Cannabidiol is the locally effective, non-psychoactive ingredient that targets exactly where conventional products often reach their limits, but without the side effects of corticosteroid products. Especially in the form of rectal suppositories like CANNEFF® SUP with hyaluronic acid, CANNEFF® SUP offers a modern approach to symptomatic relief and mucous membrane care. CBD and hyaluronic acid are generally very well tolerated. In very acute or heavily bleeding cases of hemorrhoids, a doctor must be consulted before using CANNEFF® SUP as a supplement. CANNEFF® SUP does not replace surgical or invasive measures. This is especially true for advanced stages (III–IV) or complications such as thrombosis or massive prolapse symptoms. In such cases, we use CANNEFF® SUP only after medical approval. CANNEFF® SUP relieves symptoms and accelerates healing after surgical procedures. It also cares for the mucous membrane, relieves pain, and itching.

Philip Schmiedhofer, MSc

Philip Schmiedhofer, MSc

Philip is the CEO and co-founder of cannhelp GmbH. With a degree in medical engineering and molecular biology, specializing in neuroscience and focusing on cannabinoids, he is recognized as an expert in the medical application of cannabinoids. As a medical device consultant, he also leads the sales of cannmedic and provides specialized advice to medical professionals. His expertise includes the development and sales of cannabinoid-based products. In research, he participates in significant basic research at the Center for Brain Research at the Medical University of Vienna. As co-founder and current CEO of cannmedic GmbH, a pioneer in the CBD medical products market, he has many years of entrepreneurial experience. Additionally, he maintains an extensive network in the industry and advises internationally operating companies in the field of medical cannabinoids.